Gujarat has found a place of pride in the field of cardiology. The government veterinary colleges, hospitals and biotechnologist are doing ground-breaking researches at Surat, Anand and Vadodara in this field and according to them this is the first of its kind of research not only in India but also abroad.

The Surat-based Concept Medical Research Private Limited (CMRPL) has applied for patent in India and the US for introducing nano particles to release drugs to block cell proliferation in the narrowed diseased coronary arteries.

Manish Doshi, president and Chief Executive Officer (CEO), CMRPL told Newsline: “There are no biotechnologists in India or in any other country who have used nanotechnology to release drugs into the diseased coronary arteries. The drugs are generally released through stents, known as Drug Eluting Stents (DES). The stents are bio-absorbable but are made of polymers. If the polymer remains in the diseased artery for long, it may result in inflammation, clotting and toxicity, thereby leading to further complications. As such, there are instances of complications arising after angioplasty.

He also explained about the advantages of releasing drugs such as Sirolymus and Heparil through use of nanotechnology. He said: “In comparison to the polymer, the size of the drug carrier will decrease to six fold thereby helping experts to overcome several complications. We have applied for a patent in India and the US. Further tests on animals will be conducted. Besides, we also have a coating technique in the stent for which CMRPL has applied for a patent.”

... contd.