Two big studies offer good news to people with high blood pressure, finding that novel ways to use cheap drugs already on the market can lower their risk of heart attacks, stroke and death—even if they are very old.

Both studies were stopped early so the surprising benefits could be made known. Doctors presented results on Monday at an American College of Cardiology conference in Chicago.

“It is never too late to start” on blood pressure drugs, said Dr Nigel Beckett of Imperial College in London, who led one study in the elderly that also was published online by the New England Journal of Medicine.

“Our idea is, if you have to add on, why not do two right off the bat” in a single pill, said Dr. Kenneth Jamerson of the University of Michigan. He led a study testing a single daily pill combining a diuretic and the ACE inhibitor benazepril versus a daily pill containing benazepril and a calcium channel blocker, amlodipine. ACE inhibitors dilate blood vessels to lower pressure. Calcium channel blockers do the same in a different way.

A total of 11,462 people in the United States and Nordic countries were given one combo or the other. Their average age was 68, and besides high blood pressure they were obese, had diabetes or other health problems. Neither they nor their doctors knew which drugs they were taking until the study was stopped in October after it was clear that people on the ACE-calcium blocker combo were doing better.

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