Roma are 13th in Serie A while their unpredictable form has also affected their European campaign where they have won three games but lost two, including an embarrassing home defeat to Cluj.

The Italians warmed up for the visit of Bordeaux with a 1-0 win over Chievo on Saturday for their fourth win in a row.

"Tuesday will be vital, a game that has captured the public's imagination," said Roma coach Luciano Spalletti.

But he could be without highly-rated Montenegran striker Mirko Vucinic, the scorer of three goals in the competition, who has a knee injury.

Roma won the first match with Bordeaux 3-1.

The only other spot in the last 16 still up for grabs is in Group B.

Jose Mourinho's Inter Milan, who have already qualified, travel to rock-bottom Werder Bremen while unfashionable Anorthosis Famagusta aim to make history by becoming the first Cypriot side in the knockout round.

They go to riot-torn Athens to face Panathinaikos needing to beat the Greeks to qualify but they will be without experienced Brazilian midfielder Savio who has a knee injury.

Elsewhere, Group C winners Barcelona, with 13 points from five games, welcome Shakhtar Donetsk who have already wrapped up the UEFA Cup place awarded to the third place finishers.

Second-placed Sporting Lisbon go to Basel in Switzerland.

Liverpool travel to PSV Eindhoven having already qualified from Group D but looking to finish in top spot.

Rafael Benitez's side have 11 points as do Atletico Madrid who go to Marseille where they face a stormy reception after a fan of the French club was jailed for three and a half years last week for attacking a policeman in the first match between the two sides.

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