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Ginkgo biloba does not prevent dementia: study

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L A Times, Washington Post Posted: Nov 20, 2008 at 2339 hrs IST
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Los Angeles, November 19: Long touted as an elixir of eternal mental acuity, the herbal extract ginkgo biloba does not prevent or delay the progression of dementia or Alzheimer’s disease, according to a clinical trial reported on Tuesday involving thousands of volunteers between the ages of 75 and 96.

The subjects swallowed round, reddish tablets twice a day for an average of more than six years, but at the end of the study, those who received ginkgo biloba were slightly more likely to be diagnosed with dementia and Alzheimer’s than their counterparts who received dummy pills.

The results, published in the Journal of the American Medical Association, are sure to disappoint the millions of people who take ginkgo in the hopes of boosting their brainpower and staving off the ravages of dementia and Alzheimer’s, which affect more than 5.2 million Americans. Alzheimer’s passed diabetes two years ago as the sixth-leading cause of death in the US, according to the Centers for Disease Control and Prevention.

“No one is more disappointed that we didn’t have any traction in slowing down the disease than the group that did the study,” said Dr Steven T DeKosky, who led the clinical trial.

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Mark Blumenthal, executive director of the American Botanical Council, said the study used the right dose of the right ginkgo extract and gave the pills a reasonable amount of time to show an effect. The fact that it did not help puts ginkgo in good company, he said.

“Let’s keep in mind that... no conventional pharmaceutical drug has shown any benefit for either preventing the onset of Alzheimer’s or dementia, or even slowing it down,” he said.

Ginkgo extract was used in ancient times to promote general wellness, said Dr Wallace Sampson, editor of the Scientific Review of Alternative Medicine. About 30 years ago, Europeans began testing its effects on the mental decline that often comes with aging.

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