President Barack Obama will hold talks on Thursday with officials of the US Chamber of Commerce, a powerful business lobby that has sparred with him on issues from taxes and climate change to healthcare.

The White House has billed the event as an opportunity for Obama to meet small business owners to discuss his healthcare overhaul and his proposals to improve small business access to credit to boost job creation.

A White House official said members of the Chamber of Commerce and the National Federation of Independent Business had been invited to the meeting.

The talks are significant given the rising tensions between the White House and the Chamber on many of Obama's signature domestic issues. Sensitive to the recent history, the chamber declined any comment ahead of Wednesday's talks and referred queries to the White House.

While we have had disagreements on some issues like regulatory reform and energy. We look forward to continuing to work with the Chamber on the many issues we agree on, including the importance of creating jobs and opportunities for small businesses, said White House spokeswoman Jen Psaki.

The meeting was expected to cover Obama's plan to help small business and his drive for healthcare reform.

Earlier this month, Obama pulled no punches when he attacked the Chamber for opposing his plans for a new consumer protection agency, saying it was spending millions of dollars on false advertising to kill it.

He said the Chamber had spent nearly half a billion dollars on lobbying over the last 10 years.

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