A Genoese Cristoforo Colombo almost certainly did exist. Archives record his birth and early life. But there is little to tie that man to the one who crossed the Atlantic in 1492. Snippets from Columbus’s life point all around the southern European coast. He kept books in Catalan and his handwriting has, according to some, a Catalonian flair. He married a Portuguese noblewoman. He wrote in Castilian. He decorated his letters with a Hebrew cartouche.

Since it seems now that the best bet for deducing Columbus’s true hometown is to look for a genetic match in places where he might have lived, hundreds of Spaniards, Italians, and even a few Frenchmen have happily swabbed their cheeks to supply cells for comparison.

“You would be proud to know that the man that goes to America the first time was Catalan,” said Jordi Colom, 51, an executive at a local television station whose saliva sample will help test the contention that Columbus was born in Catalonia, the once-independent eastern region of modern Spain that still fosters its own language, culture and designs on independence.

No chance, said Renato Colombo, 62, a retired Italian engineer who proffered his DNA to reassert his nation’s hold on the status quo. “It has never been in doubt that he was from Liguria,” the region in northwest Italy of which Genoa is the capital, he insisted.

Colom and Colombo are both “Columbus” in their native tongues. And along with their names, each inherited from his father a Y chromosome — a sliver of DNA passed exclusively from father to son - which would have been virtually unchanged since the 15th century. A Columbus match to either man’s Y chromosome would tie him to that paternal line’s Italian or Catalonian home.